FDA on Breast Implants & very rare ALCL (Lymphoma)
Posted in the Chattanooga Forum
#1 Apr 20, 2012
The PIP cosmetic surgery disaster was triggered, when a woman who had PIP breast implants contracted Anaplastic Large Cell Lymphoma and died. This happened in November 2010. The FDA issued this alert on January 26, 2011. The French government recommended on December 23, 2011 that women in France seek removal of these breast implants. There may be an estimated 500,000 woman with PIP implants today.
ALCL is exceedingly rare in women with and without breast implants. According to the National Cancer Institute, an estimated 1 in 500,000 women per year in the U.S. is diagnosed with ALCL. ALCL in the breast is even rarer. Approximately 3 in 100 million women per year in the U.S. are diagnosed with ALCL in the breast.
#2 Apr 23, 2012
Impacted here: Does anyone think theres a connection between breast implants and ALCL?
Mrs. Susan Grieve, a 40 years old PIP implant mum, has been recently diagnosed with anaplastic large cell lymphoma, a rarest but the most aggressive form of cancer. She is from Edinburgh and is claiming that her Poly Implant Prothese (PIP) implants have caused her illness and she and her family has decided to sue a manslaughter case against the manufacturer company.
Mrs. Grieve has clearly mentioned in her latest statement that she has suffered the form of cancer after one of her PIP breast implants burst, which forced the cancer to spread rapidly through her body. One more death occurred last year from the same cancer of Mr. Edwige Ligoneche, 53. Unfortunately, Susan is also suffering from the same cancer now.
#3 Apr 23, 2012
For the record, below find the current translated results for the phase "ALCL & PIP Implants" by language-per Google.
Language Translated query
French ALCL & Implants PIP 1,270,000 results
Italian ALCL & Impianti PIP 251,000 results
Spanish ALCL y los implantes PIP 121,000 results
English ALCL & PIP Implants 56,200 results
The French are showing much concern over this issue and maybe for a very good reason too!
#4 Apr 25, 2012
For the record today,find below the current translated results for the phase "ALCL & PIP Implants" by language-per GoogleTranslated results for pip implants & ALCL
Language Translated query
French implants PIP & AlCl 1,260,000 Spanish los implantes PIP y ALCL 179,000
Italian protesi pip e AlCl 59,200
English pip implants & ALCL 117,000
Did you know there are around 80 million people who speak French and 362 million, who speak English, an interesting poundance...no.
#5 May 1, 2012
After examining a range of data, the UKs Medicines and Healthcare products Regulatory Agency (MHRA) found that there was insufficient evidence of any association between PIP implants and cancer. However, the implants have remained under scrutiny, particularly since a French woman with the implants died of a rare form of cancer known as ALCL.
#6 May 8, 2012
Translated pages results for the phase PIP & ALCL -
Language Translated query
Italian PIP & ALCL - 1,730,000 results
French PIP & ALCL - 10,200 results
English PIP & ALCL - 510,000 results
Spanish PIP y ALCL- 2,020,000 results
Sorry about the earlier mistakes on this query
#7 May 17, 2012
Just went for my first counseling session with my cosmetic surgeon, he ne thanksver mentioned anything about this at all! Just kept telling me how much better I would feel about myself. Think I shall re-think this entire idea.
#8 May 22, 2012
Woman dignosed with anaplastic large cell lymphoma discussion board.
#9 May 30, 2012
Impacted here: Hummm both Silicone and Saline, maybe linked to ALCL- could that possibly mean: its the implant shell and not what its filled with?
According to Professor Chris Baggoley, Chief Medical Officer for the Australian Government.
All silicone gel-filled breast implants are considered high risk medical devices
Although Professor Baggoley states that there is no evidence of increased breast cancer risk or connective tissue diseases; he does state that there is a small possible link between silicone breast implants and a rare cancer called Anaplastic Large Cell Lymphoma (ALCL).
"Again, there is currently no evidence to suggest that saline-filled breast implants are linked to an increased risk of breast cancer or connective tissue disease; however, there is evidence that they may be linked to ALCL."
"In addition, according to the FDA, the link between breast implants and ALCL may not be a coincidence: as ALCL tends to be located in the region immediately surrounding the implant. Furthermore, those with ALCL and breast implants tend to exhibit a different phenotype, T-cell lymphoma, to those with ALCL and no implants, B-cell."
#10 Jun 16, 2012
Sadly Susan Grieve died of ALCL on the 3rd of June. Her family will surely continue the fight against those responsible for manufacturing and using non surgical grade implants.
#11 Jun 18, 2012
Deepest condolences for this loss of life. She leaves behind: beloved mum to Craig and Alix, nana to Olivia, much loved daughter to Alec and Iris, sister to Sandra and Stewart, sister-in-law to Lee and Eck, loving auntie to Hannah, Rachel and Conor, partner to Andy.
#12 Jul 10, 2012
Impacted here:My mum paid top dollar for her operation,£5000, but she ended up with £50 PIPs."
#14 Aug 30, 2013
Updated 8/19/2013: "The FDA has identified a possible association between breast implants and the development of anaplastic large cell lymphoma (ALCL), a rare type of non-Hodgkins lymphoma."
#15 Aug 30, 2013
Sorry forgot the link for the above.
#16 Nov 5, 2013
PIP implant breast cancer link ruled out
Wed, 30 Oct 2013 13:33:00 EST
Faulty breast implants widely known as PIP (Poly Implant Prosthese) were back in the news today, with the release of a new report that found that women who have the faulty implants are not at higher risk of cancer. Breast implants are liable to split (rupture). Concerns had been raised that PIP implants, which contain industrial silicone rather than medical-grade fillers, would expose women to potentially toxic elements if they ruptured. It was believed that this could then lead to cancer. However, a new European Commission scientific report suggests that ruptured PIP implants do not cancer. The report also found that there is no convincing evidence to justify routinely removing intact PIP implants. However, it says concerns about the high rupture rates associated with PIP implants means women who have these implants should be regularly examined by a doctor. About 47,000 British women in the UK are thought to have the implants
#17 Dec 11, 2013
The first real concern about ALCL in breast implant patients arose out of a study conducted in the Netherlands and published in the Journal of the American Medical Association in 2008. Study investigators concluded that the odds ratio for ALCL linked with breast prostheses was 18.2. "It meant you were 18 times more likely to develop ALCL of the breast if you had (breast) implants," Dr. Wanzel says.
Subsequent studies have not found similar rates of risk of developing ALCL in women who have breast implants. In these investigations, the odds ratio has been just under or just above 1, meaning that there is no increased risk to breast implant patients. In the largest cohort to date, there were more than 43,000 patients, and the relative risk was 0.89, Dr. Wanzel says.
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