Beware of dentist sneaking unknown implants into your mouth or aem!
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#1 Jul 2, 2014
Doctors invent tooth implant that delivers daily dose of medicine
By FIONA MACRAE
Last updated at 22:02 26 February 2007
A drug-filled tooth implant which releases medicine when the patient needs it could mean people never forget to take important medication.
Small enough to fit inside two artificial molars at the back of the mouth, the Intellidrug device is programmed to release medicine at set times throughout the day and night.
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Its creators hope it will help people such as Alzheimer's sufferers, who often find it hard to remember to take their medication.
Timed release during the night would also keep blood pressure - which tends to be at its highest in the early hours - in check.
The device, which could be on the market in as little as three years, is also likely to appeal to those who find it hard to swallow tablets or who don't like injections.
Dr Thomas Velten (CORR), of the Fraunhofer Institute for Biomedical Technology in Germany, one of 15 research bodies collaborating on Intellidrug, said: "It is important for some conditions that there is a constant level of drug in the blood.
"With this system, we can time the dosage to take place - even when the patient is sleeping.
"We can programme the time when the drug is to be administered and the exact amount needed. This means we can keep a constant level of the drug in the blood and we can easily adjust the dosage in line with the patient's needs, dependent on sex or weight."
Held in place with a combination of clips and dental fixative, the implant contains a reservoir packed with the drug in tablet-form.
When saliva seeps into the device, the drug dissolves to form a solution, which is pushed out of a valve at the other end at pre-programmed times.
Once in the mouth, the drug is absorbed into the body through the thin linings on the insides of the cheeks.
Such rapid absorption into the bloodstream should increase the effectiveness of drugs would be broken down by the liver and by acid in the stomach if swallowed.
Powered by battery, the device is kept in check by two electronic sensors, which detect how much drug is being released and how much is left.
The data collected by the sensors is transmitted to the patient's doctor by wireless link, allowing the doctor to adjust the dose remotely, or simply book in an appointment to refill the reservoir.
It is thought the reservoir will need to be topped up around every two weeks, although the timing will vary from patient to patient.
Already successfully tested on pigs, the device is due to be tested on humans for the first time this autumn and could be on the market by 2010.
It is still unclear how much it will cost. It is thought that most of those who use it will be elderly, allowing it to simply be slotted into the gap left by missing teeth.
And hear is the facts
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Now for another interesting tooth development!
British experts agreed there is a need for such a device. Professor Clive Ballard, of the Alzheimer's Society, said: "Compliance of important medication can be a problem for people with Alzheimer's disease, especially in the latest stages.
"This new area of research could possibly represent an important way of delivering medication safely and effectively."
Read more: http://www.dailymail.co.uk/sciencetech/articl...
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#2 Jul 2, 2014
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