Topix Chitown Regulars

Since: Mar 09

Miami, FL

#75087 Oct 24, 2012
RedheadwGlasses wrote:
Gender guesser:
http://www.hackerfactor.com/GenderGuesser.php
Paste in a post and it will tell you what it thinks the gender is and whether the person is weak or strong based on whether it's casual or formal or something like that.
Cool!

“...,to wit”

Since: Jun 09

Location hidden

#75088 Oct 24, 2012
These are for EDog- Be careful what you rant about.

Part I
AP

1:24 p.m. CDT, October 24, 2012
NEW YORK (AP) Scientists in Oregon have created embryos with genes from one man and two women, using a provocative technique that could someday be used to prevent babies from inheriting certain rare incurable diseases.

The researchers at Oregon Health & Sciences University said they are not using the embryos to produce children, and it is not clear when or even if this technique will be put to use. But it has already stirred a debate over its risks and ethics in Britain, where scientists did similar work a few years ago.

Ads by GoogleThe British experiments, reported in 2008, led to headlines about the possibility someday of babies with three parents. But that's an overstatement. The DNA from the second woman amounts to less than 1 percent of the embryo's genes, and it isn't the sort that makes a child look like Mom or Dad. The procedure is simply a way of replacing some defective genes that sabotage the normal workings of cells.

The British government is asking for public comment on the technology before it decides whether to allow its use in the future. One concern it cites is whether such DNA alteration could be an early step down a slippery slope toward "designer babies" ordering up, say, a petite, blue-eyed girl or tall, dark-haired boy.

Questions have also arisen about the safety of the technique, not only for the baby who results from the egg, but also for the child's descendants.

In June, an influential British bioethics group concluded that the technology would be ethical to use if proven safe and effective. An expert panel in Britain said in 2011 that there was no evidence the technology was unsafe but urged further study.

Laurie Zoloth, a bioethicist at Northwestern University in Evanston, Ill., said in an interview that safety problems might not show up for several generations. She said she hopes the United States will follow Britain's lead in having a wide-ranging discussion of the technology.

While the kind of diseases it seeks to fight can be terrible, "this might not be the best way to address it," Zoloth said.

Over the past few years, scientists have reported that such experiments produced healthy monkeys and that tests in human eggs showed encouraging results. The Oregon scientists reported Wednesday that they have produced about a dozen early human embryos and found the technique is highly effective in replacing DNA.

The genes they want to replace aren't the kind most people think of, which are found in the nucleus of cells and influence traits such as eye color and height. Rather, these genes reside outside the nucleus in energy-producing structures called mitochondria. These genes are passed along only by mothers, not fathers.

“...,to wit”

Since: Jun 09

Location hidden

#75089 Oct 24, 2012
Part II

About 1 in every 5,000 children inherits a disease caused by defective mitochondrial genes. The defects can cause many rare diseases with a host of symptoms, including strokes, epilepsy, dementia, blindness, deafness, kidney failure and heart disease.

The new technique, if approved someday for routine use, would allow a woman to give birth to a baby who inherits her nucleus DNA but not her mitochondrial DNA. Here's how it would work:

Doctors would need unfertilized eggs from the patient and a healthy donor. They would remove the nucleus DNA from the donor eggs and replace it with nucleus DNA from the patient's eggs. So, they would end up with eggs that have the prospective mother's nucleus DNA, but the donor's healthy mitochondrial DNA.

In a report published online Wednesday by the journal Nature, Shoukhrat Mitalipov and others at OHSU report transplanting nucleus DNA into 64 unfertilized eggs from healthy donors. After fertilization, 13 eggs showed normal development and went on to form early embryos.

The researchers also reported that four monkeys born in 2009 from eggs that had DNA transplants remain healthy, giving some assurance on safety.

Mitalipov said in an interview that the researchers hope to get federal approval to test the procedure in women, but that current restrictions on using federal money on human embryo research stand in the way of such studies.

The research was funded by the university and the Leducq Foundation in Paris.

Dr. Douglass Turnbull of Newcastle University in Britain, whose team has transplanted DNA between eggs using a different technique, called the new research "very important and encouraging" in showing that such transplants could work.

But "clearly, safety is an issue" with either technique if it is applied to humans, he said.

“...,to wit”

Since: Jun 09

Location hidden

#75090 Oct 24, 2012
Part I

This is for Edog- Be Careful what You Rant

MALCOLM RITTER

Associated Press

AP

1:24 p.m. CDT, October 24, 2012
NEW YORK (AP) Scientists in Oregon have created embryos with genes from one man and two women, using a provocative technique that could someday be used to prevent babies from inheriting certain rare incurable diseases.

The researchers at Oregon Health & Sciences University said they are not using the embryos to produce children, and it is not clear when or even if this technique will be put to use. But it has already stirred a debate over its risks and ethics in Britain, where scientists did similar work a few years ago.

Ads by GoogleThe British experiments, reported in 2008, led to headlines about the possibility someday of babies with three parents. But that's an overstatement. The DNA from the second woman amounts to less than 1 percent of the embryo's genes, and it isn't the sort that makes a child look like Mom or Dad. The procedure is simply a way of replacing some defective genes that sabotage the normal workings of cells.

The British government is asking for public comment on the technology before it decides whether to allow its use in the future. One concern it cites is whether such DNA alteration could be an early step down a slippery slope toward "designer babies" ordering up, say, a petite, blue-eyed girl or tall, dark-haired boy.

Questions have also arisen about the safety of the technique, not only for the baby who results from the egg, but also for the child's descendants.

In June, an influential British bioethics group concluded that the technology would be ethical to use if proven safe and effective. An expert panel in Britain said in 2011 that there was no evidence the technology was unsafe but urged further study.

Laurie Zoloth, a bioethicist at Northwestern University in Evanston, Ill., said in an interview that safety problems might not show up for several generations. She said she hopes the United States will follow Britain's lead in having a wide-ranging discussion of the technology.

While the kind of diseases it seeks to fight can be terrible, "this might not be the best way to address it," Zoloth said.

Over the past few years, scientists have reported that such experiments produced healthy monkeys and that tests in human eggs showed encouraging results. The Oregon scientists reported Wednesday that they have produced about a dozen early human embryos and found the technique is highly effective in replacing DNA.

The genes they want to replace aren't the kind most people think of, which are found in the nucleus of cells and influence traits such as eye color and height. Rather, these genes reside outside the nucleus in energy-producing structures called mitochondria. These genes are passed along only by mothers, not fathers.

Since: Jan 10

Location hidden

#75091 Oct 24, 2012
j_m_w wrote:
<quoted text>
Cool!
But you have to have 300 words in the post to use the program, so we can test Sub.

“The two baby belly, please!”

Since: Sep 09

Evanston IL

#75092 Oct 24, 2012
Can anyone explain to me why people keep paying attention to Honey Boo Boo?

As far as I can tell, because I've only seen pictures and the blurbs with them, she's a pudgy, ill-mannered brat.

And I'm tired of seeing her everywhere.

Since: Feb 08

Location hidden

#75093 Oct 24, 2012
squishymama wrote:
Can anyone explain to me why people keep paying attention to Honey Boo Boo?
As far as I can tell, because I've only seen pictures and the blurbs with them, she's a pudgy, ill-mannered brat.
And I'm tired of seeing her everywhere.
When I first started hearing the name I thought it must be some new stupid cartoon show.
I was right.

Toj

“Where is Everyone?”

Since: Jul 12

Location hidden

#75094 Oct 24, 2012
NWmoon wrote:
<quoted text>When I first started hearing the name I thought it must be some new stupid cartoon show.
I was right.
Ha! I don't watch her but I know way too much just b/c of commercials and her being on all kinds of programs. That kid is going to be so messed up before she's 14.

“reign in blood”

Since: May 09

Wilmington, IL

#75095 Oct 24, 2012
PEllen wrote:
These are for EDog- Be careful what you rant about.
Part I
AP
1:24 p.m. CDT, October 24, 2012
NEW YORK (AP) Scientists in Oregon have created embryos with genes from one man and two women, using a provocative technique that could someday be used to prevent babies from inheriting certain rare incurable diseases.
The researchers at Oregon Health & Sciences University said they are not using the embryos to produce children, and it is not clear when or even if this technique will be put to use. But it has already stirred a debate over its risks and ethics in Britain, where scientists did similar work a few years ago.
Ads by GoogleThe British experiments, reported in 2008, led to headlines about the possibility someday of babies with three parents. But that's an overstatement. The DNA from the second woman amounts to less than 1 percent of the embryo's genes, and it isn't the sort that makes a child look like Mom or Dad. The procedure is simply a way of replacing some defective genes that sabotage the normal workings of cells.
The British government is asking for public comment on the technology before it decides whether to allow its use in the future. One concern it cites is whether such DNA alteration could be an early step down a slippery slope toward "designer babies" ordering up, say, a petite, blue-eyed girl or tall, dark-haired boy.
Questions have also arisen about the safety of the technique, not only for the baby who results from the egg, but also for the child's descendants.
In June, an influential British bioethics group concluded that the technology would be ethical to use if proven safe and effective. An expert panel in Britain said in 2011 that there was no evidence the technology was unsafe but urged further study.
Laurie Zoloth, a bioethicist at Northwestern University in Evanston, Ill., said in an interview that safety problems might not show up for several generations. She said she hopes the United States will follow Britain's lead in having a wide-ranging discussion of the technology.
While the kind of diseases it seeks to fight can be terrible, "this might not be the best way to address it," Zoloth said.
Over the past few years, scientists have reported that such experiments produced healthy monkeys and that tests in human eggs showed encouraging results. The Oregon scientists reported Wednesday that they have produced about a dozen early human embryos and found the technique is highly effective in replacing DNA.
The genes they want to replace aren't the kind most people think of, which are found in the nucleus of cells and influence traits such as eye color and height. Rather, these genes reside outside the nucleus in energy-producing structures called mitochondria. These genes are passed along only by mothers, not fathers.
I fully support stem-cell research, I'm opposed to "designer" babies (people aren't dogs) but see nothing wrong with filtering out certain diseases or malfunctioning genes.

Honey Boo WHO?

“Fort Kickass”

Since: Sep 09

Bloomington, IL

#75096 Oct 24, 2012
edogxxx wrote:
<quoted text>

Honey Boo WHO?
Don't cry; we still mostly like you.

Since: Jan 10

Location hidden

#75097 Oct 24, 2012
I feel sorry for her. She's, waht, 5? 6? Her mother is HORRID.

I only know who they are because Anderson Cooper had the pageant moms/daughters on his show, and made the moms dress up like they make their daughters dress up. You know, like hookers. The moms didn't like it, tried to justify that it's different with their little girls because they're children and innocent, blah blah blah.

These mothers are the same pieces of trash who think it'd be funny for a 10yo girl to dress up as a hooker for halloween and a 12yo boy to dress up as a pimp.

Idiots.

Since: Mar 09

United States

#75098 Oct 24, 2012
NWmoon wrote:
<quoted text>When I first started hearing the name I thought it must be some new stupid cartoon show.
I was right.
HAHA!

Ang, she's 7 now. Her 16-yo old half-sister recently gave birth. Their mom is 33. Yeah.

Since: Jan 10

Location hidden

#75099 Oct 24, 2012
Okay, question for you guys, and for you women, too, as far as what you think your guy would say.

Would you rather never have cheese the rest of your life, or never have BJs?

I had dinner at a friend's house tonight, and apparently this question is going around. Friend's boyfriend said he'd go without BJs. I said Nick would say the same thing.

I called Nick when I got home. He didn't even hesitate. He can't live without cheese. Ha!

Since: Jan 10

Location hidden

#75100 Oct 24, 2012
I told my friends, "Hell, I just did that with nick last night, and you'd asked him five minutes later, he would have chosen to go go without another one! And I'm good!" :)

“Fort Kickass”

Since: Sep 09

Bloomington, IL

#75101 Oct 24, 2012
j_m_w wrote:
<quoted text>HAHA!

Ang, she's 7 now. Her 16-yo old half-sister recently gave birth. Their mom is 33. Yeah.
I couldn't believe she's younger than me.'Murica!
Anonymous

Plant City, FL

#75102 Oct 24, 2012
My methodologists liked my research questions! Stoked--they are picky about those. They must be right before moving on. Yippee...

And I won (again) in fantasy football. 2nd place...

“I Am Mine”

Since: Dec 08

Location hidden

#75103 Oct 24, 2012
RedheadwGlasses wrote:
Okay, question for you guys, and for you women, too, as far as what you think your guy would say.
Would you rather never have cheese the rest of your life, or never have BJs?
I had dinner at a friend's house tonight, and apparently this question is going around. Friend's boyfriend said he'd go without BJs. I said Nick would say the same thing.
I called Nick when I got home. He didn't even hesitate. He can't live without cheese. Ha!
Only thing I eat with regularity that would be irrepairably changed by the absence of cheese is pizza. Everything else,I could easily forgo cheese.

Since: Jan 10

Location hidden

#75105 Oct 24, 2012
Matilda77 wrote:
<quoted text>
I couldn't believe she's younger than me.'Murica!
Well, that means you have time to catch up to her accomplishments. Slacker.

“Fort Kickass”

Since: Sep 09

Bloomington, IL

#75106 Oct 24, 2012
RedheadwGlasses wrote:
<quoted text>Well, that means you have time to catch up to her accomplishments. Slacker.
I have wasted my life! And I only have one chin!

“reign in blood”

Since: May 09

Wilmington, IL

#75108 Oct 25, 2012

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