In a court of the law the moment a witness responses or makes any statement they have waived their right to claim the fifth.<quoted text> Making a statement is not the same as taking the stand. In court proceedings both, the defendant or lawyer, & the prosecutor make opening statements. Neither are taking the stand therefore, not subject to the 5th amendment laws at that time. Had she taken the stand & pled her innocence, then when asked questions pertaining the case tried to invoke her 5th amendment right, she couldn't because she already had given them up when she took the stand & testified to her innocence. Therefore she would be forced by law to answer the questions or suffer a jail cell until she does answer them!
The lawyer wasn't talking-the witness was.