Blood thinner Coumadin gets black box warning over fatal bleedi...

There are 20 comments on the Oct 9, 2006, NewsTarget.com story titled Blood thinner Coumadin gets black box warning over fatal bleedi.... In it, NewsTarget.com reports that:

U.S. health officials announced on Friday that drug maker Bristol-Myers Squibb has added a black box warning to its blood-thinning drug Coumadin warning of possible "major or fatal bleeding." According to the ...

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ron

Sykesville, MD

#1 Jan 1, 2007
what symptoms should one watch for
vesta

Scottsdale, AZ

#2 Jan 2, 2007
just looking at the article, maybe some symptoms to look for are easy bruising, trouble clotting, and faintness/dizziness. Look for signs of blood loss. Thats all I can think of, I would ask the doctor to be certian, they would know best, in no way should this be taken as medical advice.
EdfromNJtoAZ

Bronx, NY

#3 Jan 20, 2007
Check swelling/pain in legs/arms, dizziness, hematoma/bruising, but don't take our word for it - This is serios stuff; my dad is sitting in an ICU, because he's bleeding internally and the crack team of docs "don't know why" he's bleeding internally. Perhaps it was because he's been taking Coumadin for 10 years & his body chemistry changed? I know he took it very seriously, so I find it hard to believe he just ignored the warning label, or whatever.
catherine

Springfield Gardens, NY

#4 Jan 24, 2007
coumadin is a very dangerous drug if not monitored carefully. My mother passed away in dec. Internal bleeding from coumadin. The dangers of this drug should be carefully explained to patients who are using it. Coumadin causes 8,000 deaths a year from internal bleeding.
karen thomas

United States

#5 Feb 6, 2007
I recently lost my brother on 1-9-07, he was shot in the leg on 10-23-06, developed a blood clot around 11-15-06, his autopsy report revealed that his pancreas hemphroged because of the coumadin he was taking. He only took the blood thinner for 4-6 weeks then he died, he had just turned 44 in November Please be careful when you are taking a blood thinner, he showed no signs at all of having problems, he felt great he had a full physical 3 days before he died and nothing showed up in his blood work that he was getting sick so PLEASE be careful
MICHELLE SD CA

United States

#6 Feb 7, 2007
My condolences to you and your family........ This drug has controlled and hurt alot of us. My prayers are with you.
karen thomas wrote:
I recently lost my brother on 1-9-07, he was shot in the leg on 10-23-06, developed a blood clot around 11-15-06, his autopsy report revealed that his pancreas hemphroged because of the coumadin he was taking. He only took the blood thinner for 4-6 weeks then he died, he had just turned 44 in November Please be careful when you are taking a blood thinner, he showed no signs at all of having problems, he felt great he had a full physical 3 days before he died and nothing showed up in his blood work that he was getting sick so PLEASE be careful
Brigitte

Lorain, OH

#7 Feb 12, 2007
My mother went to the hospital for an irregular heart beat and the surgeon wanted her on coumadin. The family doctor said no because in 1998 she suffered a brain anurism and thank God she recovered. Needless to say she was sent home with 2 blood thinners including a shot of Lovenox she had to give herself 2x a day and coumadin. She came home Saturday evening Feb 3 and by Tues Feb 6 she had to have emergency brain surgery because of bleeding on the brain. She is now recovering at The Cleveland Clinic and all we can do is pray that she comes out of this. She is in a coma state. This is not a miracle drug and I think after reading all these forums alot of checking needs to take place before putting someone on this stuff.
catherine

Springfield Gardens, NY

#8 Feb 12, 2007
ron wrote:
what symptoms should one watch for
Ron,
I know brusing is one symptom, please please talk to your dr or who ever prescribes and monitors your coumadin. Go to coumadin web sites and read up as much as you can about this drug To keep yourself safe.
Frank kordewiner

Courtenay, Canada

#9 Feb 19, 2007
EdfromNJtoAZ wrote:
Check swelling/pain in legs/arms, dizziness, hematoma/bruising, but don't take our word for it - This is serios stuff; my dad is sitting in an ICU, because he's bleeding internally and the crack team of docs "don't know why" he's bleeding internally. Perhaps it was because he's been taking Coumadin for 10 years & his body chemistry changed? I know he took it very seriously, so I find it hard to believe he just ignored the warning label, or whatever.
hi - have been going to emerg twice in 14 days for bleeding in my shoulder area - patches of black and blue are about 3x5 inches round- have had no injury in this area - yet doctor shake their heads and can't believe the size of bruising - ask me to get tylonol for shoulder pain (joint)- and pushed me out of the door..." sort to speak". Have seen my family doctor - he ordered X-ray and ultra sound - sofar hospital has not responded yet - I am 76 years old and
do not know what to do at this moment to handle this situation. The heavy bruising has no been at least for 3 weeks and really looks scary.
I have been on Coumadin for 4 years now because of history of blood clots -(diagnosed Factor V Leiden). My target zone between 2.5 and 3.0 is checked every 2 weeks and seems to be ok.

feel sorry for your dad.
Janelle

Willoughby, OH

#10 Mar 14, 2007
Brigitte wrote:
My mother went to the hospital for an irregular heart beat and the surgeon wanted her on coumadin. The family doctor said no because in 1998 she suffered a brain anurism and thank God she recovered. Needless to say she was sent home with 2 blood thinners including a shot of Lovenox she had to give herself 2x a day and coumadin. She came home Saturday evening Feb 3 and by Tues Feb 6 she had to have emergency brain surgery because of bleeding on the brain. She is now recovering at The Cleveland Clinic and all we can do is pray that she comes out of this. She is in a coma state. This is not a miracle drug and I think after reading all these forums alot of checking needs to take place before putting someone on this stuff.
My prayers are with your family. I recently lost my father due to these blood thinners. My father had a mild heart attack and had surgery to unblock an artery. The surgery went fine. He was up and talking to us after the surgery. The cardiologist said he would be able to come home the next day because the surgery was so successful. We left the hospital only to get a call hours later to return because he slipped into a coma. The blood thinners had caused a major bleed in his brain. They tried to do surgery to drain the blood on his brain but it was unsuccessful. He died the very next day after the heart surgery. The day he was supposed to come home. We weren't even told of the dangers. This drug should be pulled off the market immediately!
Diane

Elgin, IL

#11 Mar 19, 2007
I'm taking Warafin since October of 2006 when I, from the long air flight from Poland developed massive blood clots to both lungs and one in my left leg. Since then I have had constant muscle pain, black circles under my eyes and I'm forever tired and have to use a cane to get around the house. There isn't a day that goes by that I feel good. Today I am not taking my pills I see the doctor tomorrow and I will tell her about all of this. When I was giving myself the shots I got so black and blue on my belly it was pitiful. Question does anyone else get the muscle pain and the dark circles under the eyes and the black and blue belly from the shots?
Gina Jackson NJ

Brooklyn, NY

#12 Mar 20, 2007
Had aortic valve replacement 3yrs ago have mechanical valve & have to take coumadin for the rest of my days. I never feel good either. Today I have bad pain in back & sides. I could sleep forever but cant cause have to take care of children. Probably wouldnt get up if I didnt have them. Found eatthisdiet for coumadin users maybe will help to feel better. So sorry to read all these stories I am always afraid something similiar would happen to me. Is it honestly normal to feel this way. Some days I can only do very minimal things its ridiculous. My cardiologist looks at me like I'm crazy. I tried working and it just never works out. I am too weak and tired. I am 38; feel like 83.
Eileen Florida

Largo, FL

#13 Mar 20, 2007
My Dad was on coumadin. We had a home health aid come in 3 times a week for blood tests. She was in on Wednesday, and the blood test was good. Friday he couldn't get out of the chair. Had no strength at all. Could only move his arms. The emergency room had to give him 3 pints of blood. His blood was as thin as water. The drug is very dangerous. I really think that it should be taken off of the market!
kristie

Australia

#14 Mar 20, 2007
im very sorry to hear of all of ur lost.after having my 3rd child i developed dvt in my left leg a day after the ceacerean.i was put on coumadin 4 six months.every time i would ask my doctor questions about my illness he would say, "UR NOT THE ONLY ONE WITH DVT OR TAKING COUMADIN,ITS NOTHING TAKE THE TABLETS AND ULL BE FINE" ??? so i thought it was nothing to worry about,i didnt know anything about this illness or this drug i was taking,i trusted my doc.but now after hearing all of ur stories it made me think,maybe its the docs not informing us properly about this drug???
DJ F

United States

#15 Mar 22, 2007
I experience lots of muscle aches and pains. I also have lots of bruising, but it pretty much whereever I bump into something. I also get knots arond the injection site. I'm also always tired and I'm pnly 26 years old. I wish you all well.
Diane wrote:
I'm taking Warafin since October of 2006 when I, from the long air flight from Poland developed massive blood clots to both lungs and one in my left leg. Since then I have had constant muscle pain, black circles under my eyes and I'm forever tired and have to use a cane to get around the house. There isn't a day that goes by that I feel good. Today I am not taking my pills I see the doctor tomorrow and I will tell her about all of this. When I was giving myself the shots I got so black and blue on my belly it was pitiful. Question does anyone else get the muscle pain and the dark circles under the eyes and the black and blue belly from the shots?
Elizabeth

Boston, MA

#16 Mar 23, 2007
> Question does anyone else get the muscle pain
> and the dark circles under the eyes and the
> black and blue belly from the shots?

Yes, I have gotten the belly and it looks so depressing I know. I noticed it was better when I always clean the area with an alcohol swab and put a band aid over the injection site. That helped the bruises be smaller. You are not alone!

RE:,"UR NOT THE ONLY ONE WITH DVT OR TAKING COUMADIN,ITS NOTHING TAKE THE TABLETS AND ULL BE FINE" - well maybe some people don't feel crappy on these drugs, but obviously many of us do. Each person is different. Again, the important part to know is if you feel tired, achy, etc. it is the drug. At least when you know what the problem is you can try to figure out what you want to do to make the situation better, you know? I don't understand why some docs seem so ignorant of the properties of this drug, when there are numerous websites full of people feeling weak, fatigued, nauseous, etc. Like we were all making it up?
Tamara

Las Vegas, NV

#17 Mar 24, 2007
Today would have been my dad's 60th birthday. He passed away two weeks ago. He was taking coumadin for 2 years because his doctor insisted he needed it. My mom noticed a change in him almost right away. He was tired and weak and not motivated at all. His appetite changed and he just wasn't the same. He would go to the doctor as ordered to get the blood tests to check his coumadin levels. He would complain of being in pain or aching and the doctor would say he was fine.

This went on and he progressively started getting worse. My mom asked him to please stop taking the coumadin after she saw they were derived from an ingrediant in rat poison. How could this be something good for him?? But he trusted his doctor and refused to stop taking it or wean himself off of it.

3 weeks ago he noticed blood coming out his mouth and his rear. They went to the hospital only to find he was bleeding internally. They kept him overnight to give him plasma and vitamin K. He also was turning yellow but the dr never checked his blood for other problems, just his coumadin levels which were high (not from taking more medicine but from what the medicine was doing to his blood. They sent him home the next day with 3 prescriptions: anxiety pills, something for joint pain and something else for pain. This was to be taken in addition to the regular dose of coumadin. My mom fired his doctor because he was not helpful.

The next day he turned even more yellow and was reeling from pain in his lower back. They rushed my dad to the hospital and later did an MRI. He had numerous growths on his liver and was experiencing total organ failure. He died 2 days later at 59 years old.

I feel robbed. I know in my heart that the combination of neglegence from his doctor to inform my dad of all the risks associated with taking this drug and giving him other options (because there ARE other options, this drug is not a last resort - my dad had a slight irregular heartbeat and lived without this drug for several years) also this doctor did not monitor my dad properly or listen to him when he would tell this dr all his symptoms.

I have been reading so much about this drug and all I read are negative things from people taking it and positive things from the doctors who prescribe it. My dad died - how many more of our loved ones have to die unneccesary deaths before someone takes action to pull this drug off the market?

If anyone wants to do something about this please let's put our heads together. My email is: dawnlight1976@aol.com
Sandy

New Cumberland, PA

#18 Mar 29, 2007
Does anyone also have very achy legs? This seems to get somewhat better when I walk a lot. I'm also tired & have stomach upset a lot of the time. Coumadin is a horrible drug. After all these years there should be a substitute.
I also read some of the symptoms can be caused by the dye in the coumadin. Any input on this?
Kay

Corryton, TN

#19 Apr 5, 2007
I feel for all the stories that I have read on this post today. My dad died 9 months ago from taking Coumadin. I live out of state from where he died, I stopped to get his Medical Records from the hospital where he passed away. He was 77 years old, and a alcoholic. He drank on a daily bases. He had been going to his Dr.'s for years, they knew his pattern. He had even treated him for DT's.

Anyway, sorry for the rambling, His INR on his last hospital visit was... 56.9!!! He had a Intercranial Bleed, end of story. I do have a question, if this is such a bad drug, why are we not seeing more Lawsuits?
richard

AOL

#20 Apr 10, 2007
I have SLE Lupus and I'm taking a blood thinner my blood is checked every two weeks and it's always off it either to high or to low. I ache a lot from my legs and I have a very large stomach I am tired all the time I'm very moody. I am taking around eight different medications.

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