Why is it when you see prisoners of war that were starved there are no fat ones that "had a disorder" and will never get thin.They CANNOT HELP IT
Tina and her daughters are all obese - but it's not their fault, it's their genes
By Cara Lee
PUBLISHED: 22:11 GMT, 20 May 2013 | UPDATED: 00:02 GMT, 21 May 2013
Nutrigenonomics is the study of the relationship between diet and specific genes, and increasingly the evidence from this work suggests that some people are born with a greater propensity to gain weight.
Scientists have identified genes that influence the intensity of your hunger pains, how well your brain gets the ‘full-up’ signals from your stomach, where your body is more likely to store fat — even your sense of taste (whether you have a genetic preference for sweet or fatty foods).
Just last week, it was revealed that a mutated version of a gene that almost a third of women are thought to have fuels the development of fatty tissue — those with it are two-and-a-half times more likely to put on more than a stone.
‘In the past five years, there have been significant developments in technology that has identified risk versions of around 70 genes people can carry, putting them at an increased risk of obesity,’ says Dr Giles Yeo, director of genomics at the Medical Research Council’s Metabolic Diseases Unit at the University of Cambridge.
Dr Yeo has identified two genes that affect the messages sent to tell our brains our stomach is full.‘Testing for the genes is cutting edge, so it’s very exciting,’ he says.‘Having a “risk” version of one of these genes won’t have an effect alone, but a number of subtle differences to many genes can amount to an increased risk of weight problems.’
‘Humans evolved to eat as much as possible because as cavemen we didn’t know when our next meal would be, says Dr Yeo. Sweet and high-fat foods have the most calories, giving us the most energy — which would have been advantageous to eat then.
‘Nowadays, of course, we don’t need to hunt but that doesn’t stop our genetic drive and the way we evolved to like sweet, fatty foods.’
But in some people, this drive is greater.‘Slight genetic changes put a person at risk of having an increased liking for food with higher energy.
‘Eating less will cause weight loss but, depending on your genetic make-up and these subtle changes, some people, such as the McConnons, find it more difficult to adhere to diets and stop eating than others.
‘When we understand more about what these genes do, we can identify at-risk people and advise them to make changes,’ says Dr Yeo.‘At the moment, these kinds of costly gene tests are not available from the NHS, although there are private companies that offer versions of them
Why were there no fat Jews in concentration camps that were "big boned" and couldn't lose weight.