Metformin (generic), Glucophage News

To study how cancer cells survive in the kind of low-glucose environment found within cancerous tumors, KA vanA Birsoy and Richard Possemato, postdoctoral researchers in Whitehead Member David Sabatini's lab, developed a system, shown here, that circulates low-nutrient media continuously around cells.

The Company expects the trial to last for approximately three months. The U.S.-based trial is intended to mirror the Company's study of BTI-320 currently enrolling patients in France.

Nursing home residents who have diabetes and chronic kidney disease are commonly given medications that are not in keeping with best practice guidelines or prescribing information, according to recently published research.

Oramed to Present Results from its Phase 2a FDA Trial with ORMD-0801 at the 2014 Diabetes Summit on April 24, 2014 Oramed Pharmaceuticals Inc. , a clinical-stage pharmaceutical company focused on the development of oral drug delivery systems, announced today that it will be presenting detailed results from its recently completed Phase 2a FDA trial ... (more)

Vipidia is a new DPP-4i for the management of Type 2 diabetes , launched in the UK with CV safety outcomes.1 Vipidia and the fixed dose combination product Vipdomet are now available in the UK.

Positive results have been reported from the sixth AWARD trial of once-weekly dulaglutide, an investigational, long-acting glucagon-like peptide 1 receptor agonist being studied as a treatment for type 2 diabetes.

In the AWARD-6 study, once-weekly dulaglutide 1.5 mg achieved the primary endpoint of non-inferiority to once-daily liraglutide 1.8 mg, as measured by the reduction of hemoglobin A1c from baseline at 26 weeks.

To compare the safety and efficacy of saxagliptin 2.5 mg twice daily versus placebo add-on therapy to metformin immediate release in patients with type 2 diabetes and inadequate glycemic control with metformin alone.

This week, Wil offers some thoughts on mixing and matching your diabetes meds. Dan, type 1 from California, writes: Since type 1 diabetics are constantly dealing all their lives with the issue of glucose release after meals, at night, and whenever from our livers, why aren't we given metformin to control this process as a standard of care? Why is ... (more)

Liraglutide, a long-acting glucagon-like peptide-1 analog, has several non- glycemic properties, but its effect on carotid intima-media thickness , a recognized marker of subclinical atherosclerosis, is still unknown.

Janssen-Cilag International NV announced today that the Committee for Medicinal Products for Human Use has adopted a positive opinion, recommending marketing authorisation in the European Union for the medicinal product VOKANAMETTM, a fixed-dose therapy combining canagliflozin and immediate release metformin in a single tablet, intended for the ... (more)

In a new study from Franciscan University in Steubenville, Ohio, researchers are exploring a possible link between metabolic defects and seizures.

This image shows the "lend a hand" illustration: an open palm facing out. The five major forms of diabetes interventions are arranged in descending order of importance from thumb to pinky.

The fruit flies have done it again. Scientists have once again used the common lab insects known as Drosophila melanogaster to study the link between epilepsy and metabolism, by way of measuring fruit fly movement with inexpensive web-cams.

The Kuehner lab demonstrates their drug-screening technique in JoVE 's peer-reviewed video format to aid other researchers in the field.

Correspondence to Pankaj Arora, MD, Division of Cardiology, University of Alabama at Birmingham, 1808 7th Ave S, BDB 201, Birmingham, AL 35294.