Imuran, Azathioprine News

Objective To prospectively determine optimal levels of 6-thioguanine nucleotide for disease remission in patients with immunobullous disease treated with azathioprine.

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Arch Dermatol. A 2009;145 :631. Azathioprine has been used by dermatologists as a corticosteroid-sparing agent for 30 years, but its mechanism and pharmacokinetics remain unclear.

Researcher Philippe Seksik, MD and colleagues presented a study at Digestive Disease Week 2009 which links thioprines to a reduced risk of advanced colon cancer in patients with ulcerative colitis .

Crohn's disease patients who received a combination of the drugs infliximab and azathioprine were more likely to have the disease go into steroid-free remission than those who received only one of the drugs, researchers say.

New long-term findings from the Phase 3b study of patients with moderately to severely active Crohn's disease having inadequate response to conventional therapies, but naive to immunomodulators and biologic therapy, were presented at Digestive Disease Week today.

Monoclonal antibodies can be safely and successfully used for the treatment of several gastroenterological disorders according to data being presented at Digestive Disease Week 2009.

Clinicians, researchers and scientists from around the world will gather for Digestive Disease Week 2009 , the largest and most prestigious gastroenterology meeting, from May 30 to June 4, 2009, at the McCormick Place Convention Center, Chicago, IL.

Hi there. My boyfriend is struggling with his Crohn's and has recently been switched from Pentasa ) to Imuran .

This month's issue of the Alimentary Pharmacology & Therapeutics examines the incidence of benign upper respiratory tract infections, HSV and HPV cutaneous infections in IBD patients treated with azathioprine.

Acute pancreatitis describes a sudden inflammatory process of the pancreas which occurs as an isolated or potentially recurrent event.

I was diagnosed with autoimmune hepatitis almost twenty years years ago. I have been quite fortunate that I have had almost perfect health throughout my time with this disease, and lucky for me, I was never sick at the time of diagnosis.

THE FDA HAS APPROVED THE FIRST NEW DRUG to treat gout in 40 years. Febuxostat reduces serum uric acid levels by blocking xanthine oxidase, an enzyme that creates uric acid by breaking down other compounds.

Tel: +44 207 269 3870; Fax: +44 207 269 3801; Email: peter.karran{at}cancer.org.uk Received December 12, 2008.

San Francisco &#8212 While all doctors face the challenge of wanting to be on the cutting edge, it&#8217s important to think about evidence-based support for therapies, says Joseph L. Jorizzo, M.D., professor ...

Mercaptopurine treatment should be considered in azathioprine intolerant patients with inflammatory bowel disease, shows the latest issue of Alimentary Pharmacology & Therapeutics .

Azathioprine is superior to budesonide in achieving and maintaining mucosal healing and histologic remission in steroid-dependent Crohn's, finds March's issue of Inflammatory Bowel Diseases .

In patients with systemic vasculitides such as Wegener's granulomatosis, azathioprine or methotrexate appear to be similarly safe in maintaining remission, according to a report in the Dec.

Christian Pagnoux, M.D., M.P.H., Alfred Mahr, M.D., Ph.D., Mohamed A. Hamidou, M.D., Jean-Jacques Boffa, M.D., Marc Ruivard, M.D., Jean-Pierre Ducroix, M.D., Xavier Kyndt, M.D., Franois Lifermann, M.D., Thomas ...