Thursday Jul 3 | New England Journal of Medicine
CORRESPONDENCE: Hydroxyurea for Sickle Cell Anemia
To the Editor: In her article on hydroxyurea for the treatment of sickle cell anemia, Platt 1 states that "the red cells of a normal adult generally contain almost 100% hemoglobin A and those of a person with ...
Effective Treatment for Sickle Cell Underused by Doctors
Uncertainties about proper use and possible long-term effects of hydroxyurea in the treatment of sickle cell anemia may be wrongly influencing doctors to avoid prescribing it to those in serious need, according ...
Hydroxyurea treatment for sickle cell underused by doctors
Uncertainties about proper use and possible long-term effects of hydroxyurea in the treatment of sickle cell anemia may be wrongly influencing doctors to avoid prescribing it to those in serious need, according ...
Exelixis Presents Clinical Data Supporting The Safety And Initial...
Main Category: Lymphoma / Leukemia Also Included In: Clinical Trials / Drug Trials ; Pharma Industry / Biotech Industry Article Date: 14 Jun 2008 - 0:00 PDT Exelixis, Inc.
A simple and sensitive ribonucleotide reductase assay.
Reviews [Write a review of this article] There are no reviews of this article Find related articles from these CiteULike users robert Find related articles with these CiteULike tags rnrs Abstract Ribonucleotide ...
Virostatics Doses First Patient In Phase IIa Trial Of VS411 For The Treatment Of HIV Infection
“We are pleased to have reached this Phase IIa milestone with the dosing of our first subjects in Pavia, Italy”
Main Category: HIV / AIDS Also Included In: Clinical Trials / Drug Trials Article Date: 14 May 2008 Virostatics, srl, a privately-held pharmaceutical company focused on the discovery and development of ... via MediLexicon
New England Journal of Medicine
Hydroxyurea for the Treatment of Sickle Cell Anemia
This Journal feature begins with a case vignette that includes a therapeutic recommendation. via New England Journal of Medicine
Lauran Neergaard: Frustrations of sickle cell
The news is grim: Ten years after government approval of the first sickle cell treatment, only a tiny fraction of patients use the drug -- despite new research showing the disease is far more painful than ... via Traverse City Record-Eagle
Some Experts Doubt Obesity Epidemic
“Being moderately plump is not a health disadvantage”
Go on, have another doughnut. According to some experts whose views are public health heresy, the jury is still out on how dangerous it is to be fat. via Hartford Courant
Problems Hamper Sickle Cell Treatment
“It's a disease that has not gotten enough attention”
The news is grim: Ten years after government approval of the first sickle cell treatment, only a tiny fraction of patients use the drug _ despite new research showing the disease is far more painful than ... via WTOP-FM Washington
Few Sickle Cell Patients Using Generic Treatment To Relieve Pain, NIH Panel Says
“You can find data that says the number of sickle cell patients is between 50,000 and 75,000, and you can find other papers that say it is between 50,000 and 120,000.”
Main Category: Pain / Anesthetics Also Included In: Blood / Hematology Article Date: 29 Feb 2008 While there is an inexpensive, generic medication that can stop severe pain and the need for blood transfusions ... via MediLexicon
Hydroxyurea for sickle cell patients
“This disease illuminates the limitations of our current healthcare system”
An independent panel convened this week by the NIH concluded that the use of hydroxyurea for sickle cell patients should be increased in adolescents and adults. via News-Medical.Net
Sickle cell drug underused, experts agree
“One of the first problems is we don't even know how many people have sickle cell disease”
An inexpensive cancer pill that can relieve the painful symptoms of sickle cell disease is used far too little and patients are needlessly suffering as a result, a panel of U.S. experts agreed on Wednesday. via Reuters
NIH Hydroxyurea Treatment For Sickle Cell Disease Conference, Feb. 25-27
Main Category: Blood / Hematology Also Included In: Conferences ; Clinical Trials / Drug Trials ; Genetics Article Date: 20 Feb 2008 - 5:00 PST newsletters For many patients, the pain and complications ... via Medical News Today
Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation.
Abstract Claspin is a homolog of Mrc1, a checkpoint protein required for the DNA replication checkpoint in yeast. via CiteULike
How I treat patients with polycythemia vera
Major predictors of vascular events are increasing age and previous thrombosis; leukocytosis and high JAK2 V617F allele burden are currently being investigated for additional prognostic value in this regard. via CiteULike
The Calcium-binding Protein S100A2 Interacts with p53 and Modulates Its Transcriptional Activity
J. Biol. Chem. , Vol. 280, No. 32. , pp. 29186-29193. Abstract Head and neck squamous cell carcinoma express high levels of the EF-hand calcium-binding protein S100A2 in contrast to other tumorigenic tissues ... via CiteULike
Confocal laser scanning microscopy of apoptosis in organogenesis-stage mouse embryos
Confocal laser scanning microscopy combined with a vital stain has been used to study apoptosis in organogenesis-stage mouse embryos. via Recent EPA Catalog Records
DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe.
EMBO J , Vol. 11, No. 4. , pp. 1343-1350. DNAReplication's tags for this article Abstract We have tested mutants corresponding to 20 DNA repair genes of the fission yeast Schizosaccharomyces pombe for their ... via CiteULike