Apr 24, 2008 | NLH Question Answering Service
Is there any evidence to support the use of sibutramine as an antidepressant?
In 2001 NHS Tayside published a prescribing review of sibutramine [1], reporting: "Sibutramine is a new anti-obesity agent, which at first glance seems little different from the antidepressant venlafaxine . via NLH Question Answering Service
NLH Question Answering Service
Is there any information on the monitoring of patients taking venlafaxine?
The CKS guideline on depression [1] reports: "Venlafaxine should not be prescribed for people with: - Uncontrolled hypertension - A high risk of serious cardiac arrhythmias - A recent myocardial infarction ... via NLH Question Answering Service
NLH Question Answering Service
Is there any evidence to support the use of mirtazapine in combination with other antidepressants?
“Newer antidepressants: there is less evidence for the efficacy and safety of newer antidepressants, such as mirtazapine, reboxetine and venlafaxine but they should be considered when first-line drugs are poorly tolerated or ineffective.”
The CKS guideline on depression [1] does not mention the use of mirtazapine in combination with other antidepressants. via NLH Question Answering Service