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Nuclear receptor signaling in macrophages.
Abstract Macrophages play diverse roles in host defense and in maintenance of homeostasis.
Study: Topical Allergy Cream Can Produce Systemic Effects in Horses
Glucocorticoid cream applied at normal doses onto healthy equine skin will be quickly absorbed into the body's system and can generate adverse systemic effects, said German researchers in a new study report.
Hypoxia inducible factor 1 alpha (HIF-1alpha) induces...
Abstract Corticosteroids are potent anti-inflammatory agents, but corticosteroid insensitivity is a major barrier for the treatment of some chronic inflammatory diseases.
A fully dissociated compound of plant origin for inflammatory gene repression
Although the gene-activating properties of GR are mainly associated with undesirable side effects, its negative interference with the activity of transcription factors, such as NF-IoB, greatly contributes to its antiinflammatory and immune-suppressive capacities.
Metabolomic biomarkers in a model of asthma exacerbation: urine nuclear magnetic resonance.
Abstract RATIONALE: Airway obstruction in patients with asthma is associated with airway dysfunction and inflammation.
Dr Parkinson was most recently research and business development consultant for Iomed Inc.
Peoplea s Pharmacy: Hazards of rheumatoid arthritis drugs
Rheumatoid arthritis is a devastating disease. Besides crippling joints, it can leave the victim exhausted and in excruciating pain.
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Treating Childhood Leukemia With Fewer Side Effects
Adding the corticosteroid dexamethasone to the treatment regimen of children with acute lymphoblastic leukemia improves survival rates and reduces the incidence of the cancer recurring, a new Dutch study shows.
Mice lacking beta6 integrin in skin show accelerated wound repair in...
Integrin alphavbeta6 is an epithelial-specific receptor that is absent from the healthy epidermis but synthesized de novo during wound repair.
Mice lacking beta6 integrin in skin show accelerated wound repair in...
Integrin alphavbeta6 is an epithelial-specific receptor that is absent from the healthy epidermis but synthesized de novo during wound repair.
Original Article: Steroid Control of Acute Middle Ear Inflammation in a Mouse Model
Carol J. MacArthur, MD ; Jacqueline M. DeGagne, BS ; J. Beth Kempton, BS ; Dennis R. Trune, PhD Objective To investigate steroids for their potential for therapeutic approaches to control otitis media.
New discovery in bronchiolitis treatment
For the first time ever, Canadian doctors have found an effective treatment for bronchiolitis.
Drug combo fights lung infection in babies
OTTAWA a ' Canadian researchers have found a combination of drugs they say could reduce the number of babies admitted to hospital for a common lung infection by 35 per cent.
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