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BIAL reports results from Phase III study of anti-epileptic Zebinix
Patients not controlled with existing anti-epileptic drugs who were given eslicarbazepine acetate as an add-on treatment experienced a mean reduction in seizure frequency of more than 61% 1. Nearly 65% of patients were classified as responders, meaning that they had achieved at least a 50% reduction in seizure frequency with Zebinix treatment.
Data Demonstrates Long-Term Reduction In Seizure Frequency With Novel ...
Data presented today, in Budapest, demonstrated that add-on treatment with the novel, once-daily anti-epileptic Zebinix resulted in a marked and sustained decrease in seizure frequency over the long-term. Results from the one-year extension of a pivotal Eslicarbazepine Acetate phase III study were presented at the International Congress for ...
Updated June 15, 2006 Pregabalin A newly approved oral drug for treating neuropathic pain from diabetic peripheral neuropathy.
Pharmaceutical Technology - Testing
Initial Solvent Screening of Carbamazepine, Cimetidine, and Phenylbutazone: Part 2 of 2
In Part 1 of this article, which appeared in the May 2009 issue of Pharmaceutical Technology, the authors described characterization methods for the functional properties and the process-dependent polymorphic flow charts of the three soft pharmaceutical materials: carbamazepine, cimetidine, and phenylbutazone.
Loophole Allows Pharmacies To Switch Drugs Without Consent
When filling a prescription, most of us expect to receive the medication the doctor ordered.
Pharmacists may be switching your meds
When you hand a pharmacist a prescription, you expect to get the medication your doctor ordered.
Pharmaceutical Technology - Ingredients
Initial Solvent Screening of Carbamazepine, Cimetidine, and Phenylbutazone
The authors describe the importance of a rapid and an abbreviated screening strategy by initial solvent screening in 20-mL scintillation vials.
Certain Epilepsy Drugs Get a Suicide Warning
The labeling for the epilepsy drugs Topamax , Lamictal , Tegretol and Trileptal come after the FDA ordered the drugs' labels be updated with warnings about suicidal risks with the medications.
FDA also required development of a medication guide, to be issued to patients each time the product is dispensed.
Epilepsy: Exposure To Valproate During Pregnancy Can Impair A Child's Cognitive Development
The study's authors say that women of childbearing age should avoid valproate as a first choice drug for the treatment of epilepsy.
New England Journal of Medicine
Cognitive Function at 3 Years of Age after Fetal Exposure to Antiepileptic Drugs
Kimford J. Meador, M.D., Gus A. Baker, Ph.D., Nancy Browning, Ph.D., Jill Clayton-Smith, M.D., Deborah T. Combs-Cantrell, M.D., Morris Cohen, Ed.D., Laura A. Kalayjian, M.D., Andres Kanner, M.D., Joyce D. Liporace, M.D., Page B. Pennell, M.D., Michael Privitera, M.D., David W. Loring, Ph.D., for the NEAD Study Group ABSTRACT Background Fetal ...
Depakote in Pregnancy May Affect Child's IQ
Studies suggest that children of mothers who take Depakote during pregnancy have lower IQs than those of women taking some other anti-seizure drugs which are used as mood stabilizers in bipolar disorder.
Epilepsy med linked to decreased IQ
Children born to women who took the epilepsy drug Depakote while pregnant had lower IQ scores than those whose moms took three other anti- seizure meds, research published this week shows.
Epilepsy Med Lower Child's IQ If Taken While Pregnant
According to a new study, children of mothers who took the epilepsy drug valproate during pregnancy had lower IQs than children of mothers who used other anti-seizure medications.
Epilepsy drug might harm fetuses
Exposure to the drug valproate in utero might hurt a child's cognition. This chart shows IQ scores for children age 3 who had been exposed to one of four antiepilepsy drugs in the womb.
Valproate exposure during pregnancy can impair a child's cognitive development
Three-year-olds whose mothers took the antiepileptic drug valproate during pregnancy had average IQs six to nine points lower than children exposed to three other antiepileptic drugs, a landmark multi-center study has found.
I.Q. Harmed by Epilepsy Drug in Utero
Pregnant women who took a popular epilepsy drug, also used to treat migraines, pain and psychiatric disorders, had children whose I.Q. scores were significantly lower than those of similar children who were not exposed to the drug, a new study has found.
Council Tackles DC's Other Drug Problem
Enjoying that tall, cool glass of carbamazepine? You may not have to for much longer, as D.C. Council is considering a bill that would help stop prescription drugs from getting into the District's drinking water.
MIP Process Used in Antiepileptic Drug Analysis
Researchers from Universitat Rovira i Virgili and the University of Strathclyde synthesized two molecularly imprinted polymers by precipitation polymerization using the antiepileptic drug carbamazepine as the template molecule and two types of crosslinking agents.
Taro Receives Final FDA Approval for Carbamazepine Extended-Release Tablets
Taro Pharmaceutical Industries Ltd. today reported that it received final approval from the U.S. Food and Drug Administration for its Abbreviated New Drug Application for Carbamazepine Extended-Release Tablets USP, 100 mg, 200 mg and 400 mg .