Avandia, Rosiglitazone News

Monique Rainford - HER HEALTH Dear Dr Rainford, I read your article in The Gleaner 's Health section on April 8 about polycystic ovarian syndrome .

In a blow to the diabetes treatment franchise of a Deerfield drug maker, the U.S. Food and Drug Administration has asked Takeda Pharmaceuticals North America Inc.

London, June 23 : A new study may help explain how a class of diabetes drugs increases the risk of heart failure.

Alun Jones, MBBS * ; Rajdeep Deb, MBBS * ; Evelyn Torsney, PhD ; Franklyn Howe, PhD ; Mathew Dunkley, MBBS, PhD ; Yanosha Gnaneswaran, MRes ; David Gaze, PhD ; Hosaam Nasr, MBBS ; Ian M. Loftus, MD, FRCS ; Mathew M. Thompson, MD, FRCS ; Gillian W. Cockerill, PhD From the Department of Cardiovascular Sciences, St George's University of London, ...

"GW Metabolic Research Laboratory" established in conjunction with Professor Cawthorne and the Clore Laboratory, University of Buckingham Porton Down, UK, 16 June 2009: GW Pharmaceuticals plc announces that it has entered into an exclusive strategic alliance with Professor Mike Cawthorne and the Clore Laboratory, University of Buckingham, focusing ...

A class of oral diabetes drugs, commonly nicknamed "glitazones." Unlike the traditional oral drugs called sulfonylureas , which lower blood glucose levels by making the pancreas secrete more insulin, the thiazolidinediones work by helping the body's tissues to use insulin more effectively and by suppressing glucose production by the liver.

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VeroScience, in collaboration with S2 Therapeutics, announced the presentation of clinical and preclinical data at the American Diabetes Association 69th Scientific Sessions on Cycloset, a novel treatment for patients with Type 2 diabetes.

Taking the diabetes medications metformin and rosiglitazone together reverses the adverse effects on bone of rosiglitazone treatment alone in an experimental model, according to a new study done in rats.

Zurich-based drug maker Roche Holding said today it will perform late-stage testing on a potential blockbuster diabetes drug.

June 8, 2009 -- For people with diabetes and stable heart disease , drug therapy works just as well as immediate bypass surgery or angioplasty to open clogged arteries , a study suggests.

The results from the phase II SYNCHRONY study are published in an article Online First and in a future edition of The Lancet .

Strict lowering of blood sugar may not have been the cause of excess deaths in a major study of patients with type 2 diabetes, U.S. researchers said on Tuesday.

Ian M. Loftus MD, FRCS, Mathew M. Thompson MD, FRCS, and Gillian W. Cockerill PhD* From the Department of Cardiovascular Sciences, St George's University of London, Cranmer Terrace, London, UK.

All study participants were stable enough not to need surgery immediately. For people with Type 2 diabetes and stable heart disease, drug treatments are as effective as angioplasty or bypass surgery in some cases, a new study suggests.

Patients with heart failure and those at risk for fractures shouldn't use Avandia, says study author Philip Home, however "when used in appropriately selected patients, [Avandia] carries no overall increase in cardiovascular risk." Photo illustration by Justin Sullivan, Getty Images FACTS ABOUT DIABETES * Nearly 24 million Americans have diabetes.

Using rosiglitazone in combination with standard diabetes treatments to lower blood glucose in type 2 diabetics does not increase the risk of cardiovascular disease or death.

Research presented at the American Diabetes Association's 69th Scientific Sessions points to increased risk for people with diabetes associated with two widely used drug classes; while another study shed new light on a different class of drugs that faced increased scrutiny from the US Food and Drug Administration .

Diabetics with stable heart disease do just as well taking drugs alone as getting quick angioplasty or bypass surgery to open blocked heart arteries, U.S. researchers said on Sunday.

RECORD trial also demonstrates durable blood sugar control over time with Avandia LONDON, RESEARCH TRIANGLE PARK, N.C., and NEW ORLEANS, June 5 /PRNewswire/ -- Clinical trial results presented today at the American Diabetes Association annual meeting show that overall rates of cardiovascular hospitalization and cardiovascular death are similar in ...