Aldactone, Spironolactone News

Most human studies testing the renoprotective benefit of adding an angiotensin receptor blocker or a mineralocorticoid receptor antagonist to a regimen based on inhibition of angiotensin-converting enzyme used relatively low doses of ACE inhibitors.

Hemodynamic Therapeutics, Inc. , a portfolio company of Cato BioVentures, announces the successful completion of its initial Phase 2 clinical study of its lead compound , a patented low-dose small-molecule investigational therapy intended for patients with treatment-resistant hypertension.

In this first study, we have focused on the binding characteristics of the mineralocorticoid receptor and the glucocorticoid receptor in the brain and pituitary of the adrenalectomized dog.

From the Department of Pharmacology, New York Medical College, Valhalla, N.Y. Correspondence to Charles T. Stier, Jr, Department of Pharmacology, Basic Science Building, New York Medical College, Valhalla, NY 10595.

From the Departments of Medicine and Physiology and Pharmacology , University of Toledo College of Medicine, Toledo, Ohio; Laboratory of Cardiovascular Science , National Institute on Aging, Baltimore, Md.

Immunoassays, rather than high-performance liquid chromatography, are the preferred technique for drug measurement because they are automated and results are obtained rapidly, aiding in patient management.

From the Departments of Medicine and Physiology and Pharmacology , University of Toledo College of Medicine, Toledo, Ohio; Laboratory of Cardiovascular Science , National Institute on Aging, Baltimore, Md.

Got a question about a health story in the news or a health topic? Here's your chance to get an answer.

Most people in the hospital for heart failure don't get sent home with a drug that could prevent a return visit, a study finds.

Most hospitalized heart failure patients are sent home without widely recommended inexpensive pills, despite a program to get more doctors to follow treatment guidelines, a study suggests.

From the Department of Cardiology , Royal North Shore Hospital, Sydney, New South Wales, Australia; Sydney Medical School, University of Sydney , Sydney, New South Wales, Australia; Department of Cardiology , Westmead Hospital, Sydney, New South Wales, Australia; Prince Henrys Medical Research Institute , Clayton, Victoria, Australia.

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Question: I was diagnosed recently with borderline hypertension. My internist has prescribed the diuretics HCT and spironolactone.

Losing weight and performing breathing exercises can also help lower blood pressure I was diagnosed recently with borderline hypertension.

BackgroundWhen used in optimal doses to treat patients with heart failure, renin-angiotensin-aldosterone system inhibitors improve clinical outcomes but can cause hyperkalemia.

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